概念 Wirchow氏(1821—1902)在100余年前提出:疾病是细胞对刺激的反应。如任何原因引起的炎症,都有白细胞浸润;炎性再生是细胞有控制的增殖,而恶性变则是无控制的增殖。这种传统病理概念奠定了细胞病理学基础。到1953年,Peters氏强调,病理过程应视为生化代谢紊乱的表现。如植物的醋酸氟毒素可转变成有害 The concept Wirchow’s (1821-1902) proposed more than 100 years ago that the disease is the response of cells to stimuli. Inflammation caused by any cause has leukocyte infiltration. Inflammatory regeneration is a controlled proliferation of cells. Malignant changes are uncontrolled proliferation. This traditional concept of pathology lays the foundation for cytopathology. By 1953, Peters emphasized that pathological processes should be considered as manifestations of biochemical metabolic disorders. Fluoride acetate, such as plants, can turn harmful