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目的:探究怀孕时间与药物流产剂量的关系,以达到提高药物流产水平的目的,以便更好的应用到临床实践中。方法:随机抽取本站从2013年5月至2015年4月接诊的100例药物流产孕妇,分成观察组和对照组,每组50例,观察组使用小剂量的复方米非司酮配伍米索前列醇进行治疗,对照组使用大剂量的复方米非司酮配伍米索前列醇进行治疗。比较观察两组药物流产孕妇的实际临床效果。结果:观察组引产成功率为98%,对照组引产成功率为86%,观察组孕妇的引产成功率明显高于对照组(P<0.05);两组药物流产孕妇晚期药物流产的成功率低于早期药物流产的成功率(P<0.05);两组孕妇的总体满意度分别为100%和90%,观察组孕妇的满意度明显高于于对照组,差异具有统计学意义(P<0.05)。结论:在药物流产孕妇中使用小剂量的复方米非司酮配伍米索前列醇进行治疗在临床上具有重要价值,不但可以提高孕妇的引产成功率,而且能够显著降低风险,避免相关后遗症的产生。
Objective: To explore the relationship between pregnancy time and medical abortion dose in order to achieve the purpose of improving the level of medical abortion in order to better apply to clinical practice. Methods: A total of 100 abortion pregnant women who were admitted to our hospital from May 2013 to April 2015 were randomly divided into observation group and control group, 50 cases in each group. The observation group was treated with low dose of compound mifepristone Supratropium for treatment, the control group using large doses of compound mifepristone with misoprostol for treatment. Compare the actual clinical effect of two groups of abortion pregnant women. Results: The success rate of induced abortion was 98% in the observation group and 86% in the control group. The success rate of induction of labor in the observation group was significantly higher than that of the control group (P <0.05). The success rate of late abortion in both groups was low (P <0.05). The overall satisfaction rate of pregnant women in two groups was 100% and 90%, respectively. The satisfaction of pregnant women in the observation group was significantly higher than that of the control group (P <0.05) ). Conclusion: It is clinically important to use small doses of compound mifepristone and misoprostol in medical abortion pregnant women, which not only can improve the success rate of pregnant women induction of labor, but also reduce the risk significantly and avoid the occurrence of related sequelae .