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目的:对不同镇静药在小儿急性惊厥中的疗效进行对比分析。方法:选取2011年3月至2015年5月治疗的小儿急性惊厥患者160例,随机进行分组,甲组患者80例,地西泮直肠给药治疗(0.3~0.5 mg/kg);乙组患者80例,应用咪达唑仑注射液滴鼻治疗(0.2~0.3 mg/kg),对治疗效果进行分析。结果:乙组患者的临床效果、急性惊厥持续时间、复发比例、不良反应均优越于甲组患者(P<0.05)。两组患者均没有发生因治疗用药导致重症不良事件发生。结论:对于小儿急性惊厥患者应用咪达唑仑滴鼻治疗,能够更好地缓解患儿的急性惊厥,效果较好,同时能够缩短急性惊厥持续的时间和复发比例,减少不良反应,安全性较高,适宜小儿急性惊厥的治疗。
Objective: To compare the efficacy of different sedatives in pediatric acute convulsions. Methods: A total of 160 children with acute convulsions treated in our hospital from March 2011 to May 2015 were randomly divided into two groups: group A (80 cases) and diazepam (0.3-0.5 mg / kg); Group B Eighty patients were treated with midazolam intranasal injection (0.2-0.3 mg / kg), and the therapeutic effect was analyzed. Results: The clinical effect, duration of acute convulsion, relapse rate and adverse reactions in group B were superior to those in group A (P <0.05). Two groups of patients did not occur due to treatment of drugs lead to serious adverse events. Conclusion: The application of midazolam nasal drops in children with acute convulsions can better relieve the acute convulsion in children, the effect is better, at the same time can shorten the duration and recurrence of acute convulsions, reduce adverse reactions, safety High, suitable for children with acute convulsions treatment.