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对３个蚕种场９０名养蚕工人的初步调查表明，７５．６％的工人因职业性接触而有不同程度的呼吸道过敏症状，其中患职业性哮喘者占１５．６％。收集、制备蚕丝、蚕尿、蛾尿和蛾毛４种变应原，用ＥＬＩＳＡ法测定养蚕工人血清特异性ＩｇＥ和总ＩｇＥ。结果表明，职业性哮喘组工人特异性ＩｇＥ水平明显高于一般过敏症状组、无症状组和对照组；养蚕工人总ＩｇＥ水平与对照组无显著差别；４种变应原中，蚕尿特异性ＩｇＥ的阳性率明显高于其它３种变应原。提示ｓＩｇＥ水平与养蚕工人职业性哮喘的发生呈正相关，蚕尿是引起职业性哮喘的主要变应原。
A preliminary survey of 90 silkworm workers in three silkworm breeding farms showed that 75.6% of workers had different degrees of respiratory allergies due to occupational exposure, with 15.6% of them suffering from occupational asthma. Four kinds of allergens, silkworm, silkworm urine, moth urine and moth hair were collected and prepared. Serum specific IgE and total IgE of sericulture workers were measured by ELISA. The results showed that the level of specific IgE in workers with occupational asthma was significantly higher than that in patients with general allergy, asymptomatic and control groups. There was no significant difference in the total IgE levels among sericulture workers among the four allergens The positive rate of IgE was significantly higher than the other three allergens. Tip sIgE levels and sericulture workers occupational asthma was positively correlated with the incidence, serotonin is the main cause of occupational asthma allergens.