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目的探讨晚期孕妇血清游离雌三醇(uE3)和β-hCG水平对胎盘功能的临床意义。方法回顾分析61例胎儿-胎盘功能异常孕妇的血清uE3和β-hCG,61例正常晚期孕妇血清uE3和β-hCG的水平作为对照。结果①3级胎盘、胎儿窘迫β-hCG的水平明显高于对照组(P<0.01),而且随着病情的加重,β-hCG的水平呈增高趋势(P<0.05)。②3级胎盘、胎儿窘迫血清uE3明显低于对照组(P<0.01)。结论uE3和β-hCG联合测定能判断胎盘功能,为临床提供判断的依据。
Objective To investigate the clinical significance of serum levels of serum free estriol (uE3) and β-hCG in placenta in late pregnant women. Methods The serum levels of uE3 and β-hCG in 61 pregnant women with abnormal fetal-placental function and the levels of serum uE3 and β-hCG in 61 normal pregnant women were retrospectively analyzed. Results ① The level of β-hCG in grade 3 placenta and fetal distress was significantly higher than that in control group (P <0.01). The level of β-hCG increased with the severity of placenta (P <0.05). ② The grade 3 placenta and fetal distress serum uE3 was significantly lower than that of the control group (P <0.01). Conclusion The combination of uE3 and β-hCG can determine the placental function and provide the basis for clinical judgment.