目的 评价钬激光经呼吸内镜介入治疗中央气道狭窄的临床效果?方法 2017年11月至2019年8月，收集应用钬激光技术治疗中央气道狭窄病患31例，临床观察并记录肿瘤的类型?临床分期?手术部位?治疗前及治疗后的气促评级?呼吸内镜下测量治疗前后气道直径，血气分析和生命征?结果 所有患者均顺利完成手术治疗，气促胸闷等症状均较前缓解?血气分析各个指标术前术后均具有统计学差异(P < 0.05)，气促评级较治疗前明显减小，呼吸频率及心率较治疗前明显改善，气道直径比治疗前明显增加，31例患者均无出现并发症?结论 钬激光“,”Objective To evaluate the efficacy of holmium laser through respiratory endoscopy treating central airway stenosis. Methods From November 2017 to August 2019， 31 patients with central airway stenosis were treated with holmium laser technology. The 31 cases of central airway stenosis caused by benign airway stenosis and malignant tumor airway stenos were confirmed by CT or bronchoscopy， and then treated with holmium laser treatment or combined freezing or balloon dilation. During the operation，clinical observation and recording of tumor types， Clinical stage， surgical site， shortness of breath rating before and after treatment， airway diameter before and after treatment under respiratory endoscopy， blood gas analysis and vital signs. Results All patients completed short-term clinical observation after operation， and symptoms such as shortness of breath and chest tightness were relieved. All indicators of blood gas analysis were statistically different before and after surgery (P <0.05). The shortness of breath rating was significantly reduced compared with that before treatment， the respiratory rate and heart rate were significantly improved compared with before treatment， and the airway diameter was significantly increased compared with that before treatment. 31 cases None of the patients had complications. Conclusion Holmium laser used in the interventional treatment of central airway stenosis is safe and feasible， and the treatment effect is obvious. It provides a new treatment method for the clinical treatment of central airway stenosis.