论文部分内容阅读
目的观察血管紧张素转换酶抑制剂(ACEI)依那普利和高选择性β1受体阻滞剂比索洛尔联合应用治疗慢性充血性心力衰竭(CHF)的临床疗效。方法采用依那普利和比索洛尔联合应用治疗CHF患者35例,并同时与常规治疗(强心利尿)35例进行比较,用药前后观察患者收缩压(SBP)、舒张压(DBP)、心率(HR)、左室收缩未内径(LVESD)、左室舒张未内径(LVEDd)及左室射血分数(LVEF)的变化。结果观察组和常规组比较差异有显著性意义(P<0.05)。结论 ACEI依那普利与高选择性β1受体阻滞剂比索洛尔联合应用是治疗慢性充血性心力衰竭(CHF)安全有效的方法。
Objective To observe the clinical efficacy of enalapril, an ACE inhibitor, and bisoprolol, a selective β1-blocker, in the treatment of chronic congestive heart failure (CHF). Methods 35 cases of CHF patients were treated with enalapril and bisoprolol combined with 35 cases of conventional treatment (cardiac diuresis). Before and after treatment, SBP, DBP, HR, LVESD, LVEDd and LVEF were measured. Results The difference between the observation group and the conventional group was significant (P <0.05). Conclusion The combination of enalapril and bisoprolol, a selective β1-blocker, is a safe and effective method for the treatment of chronic congestive heart failure (CHF).