From the studies of ore deposit geologic settings, sulfur isotopes, lead isotopes, carbon isotopes and oxygen isotopes, fluid inclusions and petrochemistry in this paper, the authorshave drawn a conclusion that the oreforming hydrothermal solutions are the high-temperaturemagmatic hydrothermal solutions for the gold ore deposit, and at the same time, the involvementof crustal materials can not be ruled out. It is the first time that the authors have proposed that the Laozuoshan gold-polymetallic ore deposit in Heilongjiang Province was formed in the calc-alkaline series environment at the margin of an active continent.