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目的:观察莫西沙星在耐多药肺结核治疗中的应用效果。方法:随机将参与研究的40例患者分成对照组和实验组,各20例。患者均患有耐多药肺结核,且于2014年12月份到2015年10月份在笔者所在医院接受治疗。对照组应用左氧氟沙星治疗,实验组应用莫西沙星治疗。比较两组患者的治疗情况。结果:实验组治疗效果理想,总有效率、治疗2个月转阴率、治疗6个月转阴率以及治疗1年转阴率比对照组高,组间差异P<0.05,有统计学意义;实验组不良反应少,安全性佳,与对照组组间差异明显,P<0.05,有统计学意义。结论:应用莫西沙星治疗耐多药肺结核,安全性以及疗效均可靠。
Objective: To observe the effect of moxifloxacin in the treatment of multidrug-resistant pulmonary tuberculosis. Methods: 40 patients were randomly divided into control group and experimental group, 20 cases each. All patients had MDR-TB and were treated at the author’s hospital from December 2014 to October 2015. The control group was treated with levofloxacin, and the experimental group was treated with moxifloxacin. Compare the treatment of two groups of patients. Results: The experimental group had good effect, total effective rate, negative conversion rate after 2 months of treatment, negative conversion rate after 6 months of treatment and negative conversion rate after 1 year of treatment. The differences between groups were significant (P <0.05) ; Experimental group less adverse reactions, safety is good, and the difference between the control group significantly, P <0.05, with statistical significance. Conclusion: The application of moxifloxacin in MDR-TB treatment is reliable and safe.