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目的探讨分析急性心肌梗死合并心力衰竭再灌注后早期应用洋地黄的近期疗效及安全性。方法选取医院急性心肌梗死合并心力衰竭再灌注后患者62例,按照入院顺序将其分为观察组与对照组各31例。对照组再灌注后3d给予洋地黄治疗,观察组再灌注后2h应用洋地黄治疗。比较2组治疗后各项指标变化及临床效果。结果2组治疗前HP、SBP、EF、LVEDV指标比较差异无统计学意义(P>0.05)。治疗后HP、SBP、EF、LVEDV水平均较治疗前降低,且观察组HP、SBP、EF、LVEDV水平较对照组降低明显;观察组总有效率为93.55%明显优于对照组的74.19%,差异均有统计学意义(P<0.05)。2组不良反应发生率比较差异无统计学意义(P>0.05)。结论急性心肌梗死合并心力衰竭再灌注后早期应用洋地黄治疗,临床效果显著,有效改善左室功能,且不良反应少,值得临床推广应用。
Objective To investigate the short-term efficacy and safety of digitalis in acute myocardial infarction with reperfusion of heart failure. Methods Sixty-two patients with acute myocardial infarction and reperfusion after heart failure were selected and divided into observation group and control group according to admission order. The control group was treated with digitalis 3d days after reperfusion and the digitalis treatment group was treated with digitalis 2 hours after reperfusion. The changes of the indexes and the clinical effects of the two groups after treatment were compared. Results There was no significant difference in HP, SBP, EF and LVEDV before treatment in the two groups (P> 0.05). After treatment, the levels of HP, SBP, EF and LVEDV were lower than those before treatment, and the levels of HP, SBP, EF and LVEDV in the observation group were significantly lower than those in the control group. The total effective rate in the observation group was 93.55% The differences were statistically significant (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion Digitalis treatment of acute myocardial infarction combined with early post-reperfusion of acute myocardial infarction has significant clinical effect, effective in improving left ventricular function and less adverse reactions, and is worthy of clinical application.