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自身免疫性溶血性贫血(AIHA)分原发性和继发性两类,其共同特性为由于红细胞自身抗体而使红细胞的存活时间缩短。根据自身抗体对温度反应的特性,AIHA又可分为温性,寒性、和双相性三型。温性自身抗体与红细胞的作用在37℃时最活跃,是最常见的一型,属于IgG免疫球蛋白;寒性自身抗体在37℃时不与红细胞结合,当温度降至接近于0℃时即与红细胞结合,属于IgM,可能由于病毒感染或支原体肺炎所引起,溶血多数为一过性;最早发现而为最
Autoimmune hemolytic anemia (AIHA) divided into two types of primary and secondary, their common characteristic is due to red blood cell autoantibodies and make the survival time of red blood cells shortened. According to the characteristics of the autoantibody response to temperature, AIHA can be divided into three types of warm, cold, and biphasic. The effect of warm autoantibodies against erythrocytes is most active at 37 ° C and is the most common type, belonging to the IgG immunoglobulin; cold autoantibodies do not bind to erythrocytes at 37 ° C and when the temperature drops to near 0 ° C That is combined with erythrocytes, are IgM, may be due to viral infection or mycoplasma pneumonia caused by hemolysis mostly transient; the first to find the most