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目的:探讨婴幼儿腹泻时血清锌含量变化,改善腹泻患儿锌营养状况,提高婴幼儿腹泻病防治水平。方法:2010年1月~2012年10月诊治的1个月至3岁腹泻患儿95例和同期门诊健康体检的271名婴幼儿为研究对象,化学发光检测法测定血锌含量,SPSS16.0统计学软件进行统计学分析。结果:健康对照组、急性腹泻组和迁延性腹泻组患儿血清锌含量(x珋±s)分别为:19.64±2.82μmol/L,13.15±3.18μmol/L,14.11±3.06μmol/L,锌缺乏发生率分别0,12.98%,5.56%,急性腹泻组及迁延性腹泻组患儿血清锌含量显著降低,锌缺乏发生率明显升高。结论:腹泻婴幼儿血清锌含量显著降低,锌缺乏发生率明显升高。婴幼儿腹泻可常规检测体内锌值,指导临床合理补锌。
Objective: To investigate the changes of serum zinc in infants and young children with diarrhea, improve the nutritional status of children with zinc diarrhea and improve the prevention and treatment of diarrhea in infants and young children. Methods: From January 2010 to October 2012, 95 children with diarrhea between 1 month and 3 years old and 271 infants and toddlers undergoing physical examination during the same period were enrolled in this study. The levels of blood zinc were determined by chemiluminescence assay. SPSS 16.0 Statistical software for statistical analysis. Results: The serum zinc levels (x 珋 ± s) in healthy control group, acute diarrhea group and persistent diarrhea group were 19.64 ± 2.82μmol / L, 13.15 ± 3.18μmol / L, 14.11 ± 3.06μmol / L, The rates of deficiency were 0, 12.98% and 5.56% respectively. Serum zinc levels were significantly decreased in children with acute diarrhea and persistent diarrhea, and the incidence of zinc deficiency was significantly increased. Conclusion: Serum zinc levels in infants and young children with diarrhea were significantly lower and the incidence of zinc deficiency was significantly higher. Diarrhea in infants and young children can routinely detect the body zinc value, to guide clinical reasonable zinc.