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目的 探讨婚前妇女弓形虫感染水平及其治疗方案。方法 采用ＥＬＩＳＡ法对宁波市１２ ２２４名婚前妇女进行了弓形虫感染检测（包括弓形虫循环抗原ＣＡｇ、特异性ＩｇＧ和ＩｇＭ 抗体）。结果 婚前妇女弓形虫总感染率为６３９％ ，其中既往感染率为３５５％ ，新近感染率为２５１％ ，混合感染率为０３３％ 。不同年份间弓形虫感染率差异有高度显著性（Ｐ＜ ００１），但不同职业间弓形虫感染率差异无显著性（Ｐ＞ ００５），且ＨＢｓＡｇ 阳性与弓形虫感染无关（Ｐ＞ ００５）；乙酰螺旋霉素在治疗婚前妇女弓形虫感染中有一定作用。结论 对婚前妇女及孕产妇弓形虫感染的筛选和管理，将有利于控制和减少先天性弓形虫病的发生。
Objective To investigate the level of Toxoplasma infection in premarital women and its treatment plan. Methods Toxoplasma gondii infection was detected in 12,224 premarital women in Ningbo City (including Toxoplasma CAg, specific IgG and IgM antibodies) by ELISA. Results The prevalence of Toxoplasma gondii in premarital women was 639%, of which the former infection rate was 355%, the second infection rate was 251%, and the mixed infection rate was 033%. The infection rates of Toxoplasma gondii in different years were highly significant (P <001), but there was no significant difference in the infection rates of Toxoplasma between different occupations (P> 0.05), and the positive of HBsAg was not related to Toxoplasma infection > 0 05); Acetylspiramycin in the treatment of pre-marital women Toxoplasma infection has a role. Conclusion The screening and management of Toxoplasma gondii infection in premarital women and pregnant women will help to control and reduce the incidence of congenital toxoplasmosis.