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目的研究与探讨宝鸡地区高龄孕妇在超声引导下进行羊膜腔穿刺术的产前诊断的安全性及应用价值。方法回顾性分析宝鸡地区2014年1月至2016年11月之间进行羊膜腔穿刺术的高龄孕妇共210例,羊水细胞进行培养分析后,对产前诊断结果、妊娠结局及流产率进行分析。结果与结论共发现异常核型14例,异常核型检出率为6.67%,其中数目异常8例,占异常核型3.81%,结构异常6例,占异常核型2.86%,穿刺术后均无流产、无其他穿刺并发症发生。
Objective To study and explore the safety and application value of prenatal diagnosis of amniocentesis in pregnant women in Baoji region. Methods A total of 210 elderly pregnant women undergoing amniocentesis in Baoji region from January 2014 to November 2016 were retrospectively analyzed. The results of prenatal diagnosis, pregnancy outcome and abortion rate were analyzed after culturing the amniotic fluid cells. RESULTS AND CONCLUSIONS: A total of 14 cases of abnormal karyotypes were detected. The detection rate of abnormal karyotype was 6.67%. Among them, 8 cases were abnormal in number, accounting for 3.81% of abnormal karyotypes, 6 cases were abnormal in structure, accounting for 2.86% of abnormal karyotypes. No abortion, no other puncture complications.