论文部分内容阅读
目的探讨老年胃肠道恶性肿瘤术后早期肠内营养和肠外营养联合应用的可行性、安全性和临床效果。方法 60例胃肠道恶性肿瘤根治性手术的老年患者,术后第1天随机分为(1)肠外营养(PN)组;(2)肠内和肠外联合营养(EN-PN)组;(3)对照组。观察在治疗过程中3组患者并发症的发生率,术后胃肠功能恢复时间及营养评定的各项指标并进行对比分析。结果对照组并发症发生率明显高于 EN-PN 组和PN组(P<0.05)。对照组术后胃肠功能恢复时间较 EN-PN 组和 PN 组明显延长。而 EN-PN 组较其它两组显著缩短(P<0.05)。EN-PN 组和 PN 组术后血清蛋白、前白蛋白、转铁蛋白和淋巴细胞总数在营养支持后均明显升高(P<0.05),体重下降缓慢。结论胃肠道恶生肿瘤根治术后早期肠内营养及肠外营养联合应用安全可行。在改善机体营养状况方面与肠外营养相似,并有促进和维护胃肠道功能的作用,且费用较低。
Objective To investigate the feasibility, safety and clinical effect of early postoperative enteral nutrition and parenteral nutrition in senile patients with gastrointestinal cancer. Methods Sixty elderly patients with radical surgery of gastrointestinal malignancies were randomly divided into (1) parenteral nutrition group (PN) on the first postoperative day; (2) enteral parenteral nutrition (EN-PN) group ; (3) control group. Observe the incidence of complication, postoperative gastrointestinal function recovery time and nutritional assessment of various indicators in the course of treatment and comparative analysis. Results The complication rate in control group was significantly higher than that in EN-PN group and PN group (P <0.05). The recovery time of gastrointestinal function in control group was significantly longer than that in EN-PN group and PN group. The EN-PN group was significantly shorter than the other two groups (P <0.05). The total number of serum albumin, prealbumin, transferrin and lymphocytes in EN-PN group and PN group were significantly increased after nutrition support (P <0.05), and body weight decreased slowly. Conclusion The combination of early enteral nutrition and parenteral nutrition after radical operation of gastrointestinal malignant tumors is safe and feasible. In improving the nutritional status of the body with parenteral nutrition similar, and to promote and maintain gastrointestinal function, and the cost is lower.