本实验研究体外证实：豚鼠组织抗原可诱导经其免疫Ｗｉｓｔａｒ大鼠Ｔ淋巴细胞特异性增殖。Ｔ细胞疫苗能诱导经此疫苗接种鼠产生抗其个体型淋巴细胞增殖。这些淋巴细胞包括ＣＤ４＋和ＣＤ８＋两类表型。经Ｔ细胞疫苗接后，Ｗｉｓｔａｒ大鼠淋巴细胞表现出对豚鼠组织抗原的特异性转化率降低。体内研究表明：Ｔ细胞疫苗接种能显著延长异种角膜植片在Ｗｉｓｔａｒ大鼠眼中的存活期，其疗效优于雷公藤甲素，接近ＣｓＡ。 The experimental study confirmed in vitro: guinea pig tissue antigen can be induced by its immune Wistar rat T lymphocyte-specific proliferation. T-cell vaccines induce production of anti-myeloid lymphocytes via this vaccinated mouse. These lymphocytes include two types of CD4 + and CD8 + phenotypes. After T cell vaccination, Wistar rat lymphocytes showed reduced specific conversion to guinea pig tissue antigens. In vivo studies show that: T cell vaccination can significantly extend the survival of heterogenous corneal graft in the Wistar rat eyes, the effect is superior to triptolide, close to CsA.