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1992年~1993年,我站门诊处置狂犬或可疑犬咬伤共1803例,采用我国现行“原代地鼠肾细胞培养人用狂犬病疫苗”试用“10日5针法”——0、3、5、7、10日各1针(肌肉注射)。观察结果如下: 1.延寿县属狂犬病老疫区,全县15个乡、镇中9个为重流行区。近年来每年需用疫苗1500人份。人被犬咬伤后,正确并及时处理伤口者仅占20%左右;而且使用疫苗又不及时,一般超过12小时。常规法免疫程序(30天注射5针)期内,疫苗存放室温30天,温度高的达30℃,对疫苗质量影响极大。 2.1991年内有3例狂犬病死亡病例。潜伏期分别为22、<30天及30天。即3例死亡病例的出现都是在常规法的第4至第5针之间或第5针注射的当天。30
From 1992 to 1993, 1803 cases of rabies or suspicious dog bites were treated in our outpatient clinic. The “5-acupuncture on the 10th of the 10th” trial of “Current Rabbit Kidney Rabies Vaccine for Primary Hamster” 5, 7, 10 each 1 needle (intramuscular injection). Observations are as follows: 1. Yanshou County rabies epidemic area, the county 15 townships, nine towns in the heavy traffic area. In recent years, the vaccine needs 1,500 people each year. People were bitten by dogs, the correct and timely treatment of wounds accounted for only about 20%; and the vaccine is not timely, usually more than 12 hours. Conventional immunization program (30-day injection of 5-pin) During the period, the vaccine stored at room temperature for 30 days, the temperature up to 30 ℃, the vaccine quality is greatly affected. 2. There were 3 deaths from rabies in 1991. The incubation period was 22, <30 days and 30 days respectively. That is, the three deaths occurred on the day of injection between the 4th and 5th stitches or the 5th stitch of the conventional method. 30