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将86例急性重症胰腺炎患者随机分为观察组和对照组各43例,两组患者均给予胃肠减压、静脉滴注抗生素等基础治疗,在此基础上观察组给予早期肠内营养支持治疗,对照组给予肠外营养支持治疗。观察两组患者感染发生率、多器官功能衰竭发生率、病死率及血清淀粉酶、C反应蛋白、血清白蛋白、血糖等临床指标的变化情况。结果观察组患者感染发生率、多器官功能衰竭发生率及病死率均明显低于对照组,具有统计学意义(P<0.05);两组患者治疗前与治疗后血清淀粉酶、C反应蛋白、血清白蛋白、血糖等临床指标组间比较,无统计学意义(P>0.05)。与肠外营养支持疗法相比,早期应用肠内营养支持疗法具有降低患者感染率、多器官功能衰竭发生率及病死率的效果,对患者预后的改善具有显著的作用。
86 cases of acute severe pancreatitis were randomly divided into observation group and control group, 43 cases in each group, both groups were given gastrointestinal decompression, intravenous antibiotics and other basic treatment, on the basis of the observation group given early enteral nutrition support Treatment, control group given parenteral nutrition support treatment. The incidence of infection, the incidence of multiple organ failure, the mortality and the changes of serum amylase, C-reactive protein, serum albumin and blood glucose were observed. Results The incidence of infection, multiple organ failure and mortality in observation group were significantly lower than those in control group (P <0.05). The levels of serum amylase, C-reactive protein, Serum albumin, blood glucose and other clinical indicators between groups were not statistically significant (P> 0.05). Compared with parenteral nutrition support therapy, early enteral nutrition support therapy has the effect of reducing the infection rate of patients, the incidence of multiple organ failure and mortality, and has a significant effect on the prognosis of patients.