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本文分析20例无严重排斥反应的肾移植患者与正常人相比血中纤连素(Fn)增高,而补体成C3、C4含量均低,但C反应性蛋白(CRP)阴性,血中肿瘤坏死因子(TNF)水平与正常人近似。肾移植术后,短期内见有CRP迅速而明显上升,而TNF早期呈明显降低,随后二者均逐渐恢复正常,C3、C4和Fn虽然均有波动,但前二者仍低于正常,后者仍高于正常水平,特别值得注意的是移植前仅有少数病人可检出巨细胞病毒(CMV)IgM/IgA抗体,但移植后2~4周所有病人CMVIgM/IgA抗体均呈阳性。
In this paper, 20 cases of renal transplant recipients without serious rejection were found to have higher fibronectin (Fn) and C3, C4 contents in blood than normal subjects, but C-reactive protein (CRP) negative, The level of necrosis factor (TNF) is similar to that of normal people. Immediately after renal transplantation, there was a rapid and significant increase of CRP, but a marked decrease of TNF in the early stage, and then both returned to normal gradually. Although C3, C4 and Fn both fluctuated, the former two were still below normal, Is still higher than normal level. Of particular note is that CMV IgM / IgA antibody was detected in only a few patients before transplantation, but CMVIgM / IgA antibody was positive in all patients 2 to 4 weeks after transplantation.