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先证者Ⅱ_7,男,53岁,胸前皮肤划破后形成一疤痕疙瘩48年。天阴时痒。体检胸前有10.5×0.2×0.6(cm)突出皮肤,厚,硬,坚韧有弹性,表面光滑、粉红色、无毛的疤痕疙瘩。家族史 4代59人,4代有类似的情况者11人。年龄最大78岁,最小6岁。均为不同原因致皮肤损伤后引起。首发病例Ⅱ_1有6子女3个发病一Ⅱ_5Ⅱ_7Ⅱ_(11)。此3人婚后,其后代Ⅲ_(12)Ⅲ_(16)Ⅲ_(24)Ⅲ_(25)Ⅲ_(26)Ⅲ_(31)和Ⅱ_(12)Ⅱ_(13)的后代Ⅳ_1发病。调查结果表明,凡双亲之一有病其后代就发病,男女均有,连续几代。其传递方式符合常染色
Proximals Ⅱ_7, male, 53 years old, formed after the chest skin cut a keloid 48 years. Itchy overcast days. Check chest with 10.5 × 0.2 × 0.6 (cm) prominent skin, thick, hard, tough and flexible, smooth surface, pink, glabrous keloid. Family history of 4 generations of 59 people, 4 generations have 11 similar cases. The oldest is 78 years and the youngest is 6 years old. Are caused by different causes of skin damage. The first case Ⅱ_1 6 children and 3 cases of a Ⅱ Ⅱ Ⅱ_7 Ⅱ_ (11). After the marriage of 3 people, their offspring Ⅲ_ (12) Ⅲ_ (16) Ⅲ_ (24) Ⅲ_ (25) Ⅲ_ (26) Ⅲ_ (31) and Ⅱ_ (12) Ⅱ_ (13) The results of the survey showed that when one of the parents became ill, their offspring were morbid, both men and women, for several generations. The transfer method consistent with the usual staining