论文部分内容阅读
目的对一起百日咳家庭聚集性发病进行调查,为研究百日咳传播特征及其防控措施提供依据。方法鼻咽拭子采用聚合酶链反应检测百日咳鲍氏杆菌DNA,血液标本采用酶联免疫吸附试验检测抗百日咳鲍氏杆菌特异毒素Ig G和Ig M抗体。结果本起百日咳家庭聚集性发病的传播方式可能为成年人→婴幼儿。结论成年人感染者在百日咳的传播中具有重要的流行病学意义,应加强对百日咳病例密切接触者的主动监测及百日咳知识的宣传教育。
Objective To investigate the incidence of pertussis familial aggregation and provide the basis for studying the transmission characteristics of pertussis and its prevention and control measures. Methods Nasopharyngeal swabs were used to detect the DNA of Bordetella pertussis by polymerase chain reaction. Antibodies against B. pertussis specific toxins Ig G and Ig M were detected by enzyme-linked immunosorbent assay in blood samples. Results The incidence of pertussis familial onset of transmission may be adults → infants and young children. Conclusion Adults infected with HIV have an important epidemiological significance in the transmission of whooping cough. The active monitoring of close contacts of pertussis patients and the publicity and education of pertussis knowledge should be strengthened.