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目的分析军队腺病毒疫情的临床特点,为临床诊断及治疗提供参考。方法收集一起军队腺病毒感染住院病人217例的临床表现、影像学检查、实验室检查等相关临床资料行回顾性统计分析。结果从三大常规及生化分析看,肺炎患者与上呼吸道感染患者比较,血红蛋白、心肌酶谱、尿液分析的变化有统计学差异(P<0.05)。从炎性指标看,大面积肺炎组(累及肺叶大于2个)与上呼吸道感染组进行比较:血沉(erythrocyte sedimentation rate,ESR)、C反应蛋白(C-reaction protein,CRP)、降钙素原(procalcitonin,PCT)差异有统计学意义(P<0.05),白细胞介素6(interleukin6,IL-6)无统计学差异。结论腺病毒感染发病急,可短期导致军内呼吸道疾病流行,多数伴有呼吸道症状,其他系统症状轻微。炎性指标明显升高、心肌酶异常、贫血、尿液分析异常为重症的临床特征,需重视。
Objective To analyze the clinical features of the military epidemic of adenovirus and provide reference for clinical diagnosis and treatment. Methods A total of 217 hospitalized patients with adenovirus infection were enrolled in the retrospective statistical analysis of clinical manifestations, imaging studies and laboratory tests. Results From the three conventional and biochemical analyzes, the changes of hemoglobin, myocardial enzymes and urinalysis in pneumonia patients were statistically different from those in patients with upper respiratory tract infection (P <0.05). From the inflammatory indicators, large area pneumonia group (involving more than two lung lobes) were compared with upper respiratory tract infection group: erythrocyte sedimentation rate (ESR), C-reaction protein (CRP), procalcitonin There was no significant difference between the two groups (procalcitonin, PCT) (P <0.05) and interleukin 6 (IL-6) Conclusions The incidence of acute adenovirus infection may shortly lead to the prevalence of respiratory diseases in the military, most with respiratory symptoms, minor symptoms of other systems. Inflammatory index was significantly increased, abnormal myocardial enzymes, anemia, abnormal urine analysis for the clinical features of severe disease, need attention.