人乳头瘤病毒(HPV)是部位特异的DNA病毒,可产生表皮和粘膜的特征性增殖。传统认为HPV感染限于外阴、肛门、阴道下段,产生乳头瘤——尖锐湿疣,后又发现宫颈处可有病毒增殖,但无乳头瘤样生长——扁平湿疣。肉眼不能发现扁平湿疣,只有用3％乙酸涂浸后才能发现,故作者将其称为亚临床型乳头瘤病毒感染。作者报道154例外生殖器和肛门湿疣或亚临床 Human papillomavirus (HPV) is a site-specific DNA virus that produces characteristic proliferation of the epidermis and mucous membranes. HPV infection is traditionally considered confined to the vulva, anus, vaginal lower segment, resulting in papilloma - condyloma acuminata, and later found that the cervix may have viral proliferation, but no papilloma-like growth - flat condyloma. The naked eye can not be found flat condyloma, only with 3% acetic acid dip can be found, so the author called it a subclinical papillomavirus infection. The authors report 154 cases of genital and anal warts or subclinical