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幼年自发性高血压大鼠（SHR）从第4周末开始至第7周末给予卡托普利60ms／ks·d治疗3周，然后停药观察血压变化。结果发现．治疗可使SHR在整个实验观察期间（8～16周）血压升高延缓3～4周。作者认为应用卡托普利治疗可延缓高血压的自然发展过程。
Pediatric spontaneous hypertensive rats (SHR) were given captopril 60 mg / ks · d for 3 weeks starting from the end of the 4th week to the end of the seventh week, and then stopped to observe the change of blood pressure. turn out. Treatment resulted in a delay of 3 to 4 weeks in SHR during the entire experimental period (8-16 weeks). The authors believe that the application of captopril treatment can delay the natural process of development of hypertension.