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目的 :多发性硬化伴周围神经病 (MultipleSclerosiswithPeripheralNeuropathy ,MS PN)临床上较少见。我们对本病的临床表现、诊断标准进行了探讨。方法 :回顾性地研究了诊断为MS伴有周围神经损害病人的临床表现、神经电生理变化。结果 :98例MS病人中 16例诊断为MS PN。其临床表现有肢体麻木、无力 ,腱反射减低等。在EMG上表现有不同程度地运动、感觉神经传导速度减低 ,波幅减低 ,远端潜伏期延长。结论 :MS PN是MS的一种特殊类型。其性别、临床表现与不伴周围神经损害的MS病人基本相似。MS PN病人的发病年龄明显较MS不伴PN者偏大。本文提出了MS PN临床诊断的参考标准。
Objective: Multiple Sclerosis with Peripheral Neuropathy (MS PN) is clinically rare. We discuss the clinical manifestations of the disease, diagnostic criteria. Methods: A retrospective study of patients diagnosed with MS with peripheral nerve damage in patients with clinical manifestations, electrophysiological changes. Results: Of the 98 MS patients, 16 were diagnosed as MS PN. The clinical manifestations of limb numbness, weakness, reduced tendon reflexes. The EMG showed varying degrees of movement, sensory nerve conduction velocity decreased, amplitude decreased, the distal latency. Conclusion: MS PN is a special type of MS. The gender, clinical manifestations and peripheral nerve damage without the MS patients are basically similar. The onset age of MS PN patients was significantly larger than that of MS patients without PN. This paper presents a reference standard for clinical diagnosis of MS PN.