系统性红斑狼疮(systemic lupus erythematosus,SLE)是一种可以累及全身多个脏器的自身免疫性疾病,该病主要影响育龄期妇女,50岁后发病的患者相对少见。多数学者认为发病年龄≥50岁为晚发性SLE[1~3]。关于晚发性狼疮肾炎的研究相对较少,多依照晚发性SLE发病年龄的标准[4~7]。以往研究显示,晚发性SLE和普通SLE在临床表现、实验室检 Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect multiple organs throughout the body and affects mainly women of childbearing age who are relatively infrequent after the age of 50 years. Most scholars believe that the onset of age ≥ 50 years of late-onset SLE [1-3]. There are relatively few studies on late-onset lupus nephritis, which is based on the age of onset of late-onset SLE [4-7]. Previous studies have shown that late onset SLE and general SLE in clinical manifestations, laboratory tests