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目的研究HBsAg阳性与肥胖的关系。方法收集体检者512人,检测HBsAg阳性者与HBsAg阴性者之间与肥胖相关的指标(如体重、BMI、腰围、腰臀比等)、及与炎症相关的指标(IL-6、CRP、TNF-α等)以及肝功能、血脂等,并研究它们之间的关系。结果与HBsAg阴性者相比,HBsAg阳性者的腰围、腰臀比显著增加,但血液中HBV-DNA阳性者和HBV-DNA阴性者腰围、腰臀比、IL-6、CRP、TNF-α等差异无统计学意义。结论在人群中,HBsAg阳性与人体朝着向心性肥胖发展具有相关性,其作用机理与HBV-DNA阳性相关性不大。
Objective To study the relationship between HBsAg positive and obesity. Methods A total of 512 physical exams were collected to detect obesity related indicators (such as body weight, BMI, waist circumference and waist-to-hip ratio) between HBsAg-positive and HBsAg-negative individuals and the indexes related to inflammation (IL-6, CRP, -α, etc.) and liver function, blood lipids, etc., and study the relationship between them. Results Compared with HBsAg-negative patients, the waist circumference and waist-hip ratio of HBsAg positive patients increased significantly, but the waist circumference, waist-hip ratio, IL-6, CRP, TNF-α, etc. in HBV-DNA positive and HBV- The difference was not statistically significant. Conclusion In population, the positive of HBsAg and the body toward the development of central obesity have a correlation, the mechanism of action and HBV-DNA positive correlation is not.