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目的:研究骨通薄膜衣片的处方组成和制备工艺。方法:以颗粒性状、制粒难度、休止角、片面光洁度、硬度、崩解时限为指标,单因素法优选片剂处方。结果:按照浸膏粉-淀粉-乳糖-微粉硅胶(1:0.5:0.4:0.1)的比例混合,85%乙醇制粒,压片、包薄膜衣。结论:骨通薄膜衣片处方合理,工艺简便易行,可达到生产要求。
Objective: To study the prescription composition and preparation technology of Gutong film coated tablets. Methods: Granule properties, granulation difficulty, angle of repose, surface smoothness, hardness and disintegration time were used as indexes. Single factor method was used to optimize the prescription of tablets. Results: According to the ratio of extract powder - starch - lactose - silica gel powder (1: 0.5: 0.4: 0.1), 85% ethanol was granulated and tabletted. Conclusion: Gutong film coated tablets reasonable prescription, process is simple and easy, can meet the production requirements.