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本文对阿麒帖传统剂型的铅硬膏和改制后的新剂型巴布剂的止痛效果进行了实验研究。结果表明,新剂型对化学刺激致痛抑制率为68.4％,铅硬膏剂型为54.8％,对照组为34.2％;新剂型对热致痛在36小时内各测定时间的抑制率均有明显提高,且高于铅硬膏。上述两项指标表明,新剂型优于麝香壮骨膏、关节镇痛膏等几种市售同类产品。剂型改进后,克服了黑膏药患者不易接受、污染衣服、使用不便等缺点,具有药效迅速、使用舒适、皮肤过敏少等优点,便于临床推广应用。
In this paper, the analgesic effect of the traditional plaster of the Amitui traditional formulation and the new formulation of the cataplasm was studied. The results showed that the inhibition rate of the new formulation on chemical stimuli was 68.4%, that of lead plaster was 54.8%, and that of the control group was 34.2%. The inhibition rate of the new formulation on heat-induced pain within 36 hours was significantly improved. And higher than lead paste. The above two indicators show that the new dosage form is superior to several commercially available similar products such as Huxiangzhuang Gugu and joint analgesics. After the dosage form is improved, it overcomes the shortcomings of patients with black plasters, such as being difficult to accept, contaminating clothes, and being inconvenient to use, and has the advantages of rapid efficacy, ease of use, and less skin allergies, and is convenient for clinical application.