经对苹果黄蚜、桃粉蚜、山楂叶螨、麦长腿红蜘蛛、麦长管蚜、烟蚜、甘蓝蚜进行室内毒力测定，硫酸烟碱对７种供试害虫均有较强的毒杀力，但其敏感性存在明显差异，以苹果黄蚜最敏感，致死中浓度（ＬＣ５０）为２２．１９ｍｇ／ｋｇ，桃蚜、甘蓝蚜最不敏感，致死中浓度分别为６７．１３ｍｇ／ｋｇ和６１．９８ｍｇ／ｋｇ。大田喷０．０６％硫酸烟碱后２４、７２ｈ的校正防效，苹果黄蚜分别为９１．２２％和９２．４５％，山楂叶螨分别为９０．８１％和９１．２３％，麦长腿红蜘蛛分别为８８．４５％和９０．７１％，具有击倒力强，药效较长的特点。 The indoor toxicity test of apple aphid, peach aphid, hawthorn spider mite, wheat long-legged spider mite, wheat aphid, myzus persicae and cabbage aphid were carried out. However, the sensitivity was significantly different. The most sensitive to the yellow apple aphid (LC50) was 22.19mg / kg, the most insensitive to Myzus persicae and cabbage aphid, and the lethal concentrations were 67.13mg / kg and 61.98 mg / kg. After field sprayed with 0.06% nicotine sulphate for 24 and 72h, the control efficacy was 91.22% and 92.45% for apple aphids and 90.81% and 91.23% for hawthorn spider mites, respectively Red spider legs were 88.45% and 90.71%, with strong knockdown, long-term efficacy.