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目的:评价半夏泻心汤加减对比单纯西药治疗反流性食管炎的效果。方法:检索中国期刊全文数据库、中国生物医学文献数据库、维普中文科技期刊数据库、万方医学期刊数据库,检索对象为半夏泻心汤及其加减方对比西药治疗反流行食管炎的临床随机对照研究。数据处理使用Revman 5.3软件进行分析。结果:纳入27篇文献,共2300名患者。结果显示,半夏泻心汤加减与西医治疗效果相比较,在总有效率[OR=3.31,95%CI(2.57,4.27),Z=9.22(P<0.00001)]、治愈率[OR=1.88,95%CI(1.53,2.31),Z=6.05(P<0.00001)]上差异具有统计学意义。结论:使用半夏泻心汤加减治疗反流性食管炎在治愈率和总有效率上均优于单纯使用西药治疗。
Objective: To evaluate the effect of Banxiaxiexin Decoction compared with western medicine in the treatment of reflux esophagitis. Methods: The Chinese Journal Full-text Database, Chinese Biomedical Literature Database, VIP Chinese Science and Technology Periodical Database, Wanfang Medical Journal Database were searched. The randomized controlled clinical trials of Banxiaxiexin Decoction and its addition and subtraction prescriptions in the treatment of reflux esophagitis the study. Data processing was analyzed using Revman 5.3 software. Results: 27 articles were included for a total of 2,300 patients. The results showed that the total effective rate [OR = 3.31, 95% CI (2.57, 4.27), Z = 9.22 (P <0.00001)], the cure rate [OR = 1.88 , 95% CI (1.53,2.31), Z = 6.05 (P <0.00001)]. Conclusion: The use of Banxiaxiexin Decoction in the treatment of reflux esophagitis cure rate and total effective rate is better than the simple use of western medicine.