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目的:对产妇妊娠结局受抗梅毒治疗以及TRUST滴度的影响进行分析。方法:纳入对象在我院接受妊娠期梅毒治疗的患者,将其作为试验组,以孕期不同的驱梅时机作为分组依据,将患者分为A组、B组、C、D,将同时段在我院接受健康体检的健康产妇作为对照组。结果:对照组新生儿死亡率、流产率等观察指标均明显低于试验组,差异可见显著意义(P<0.05)。A、B、C组不良妊娠结局率明显低于D组(P<0.05),且A组不良妊娠结局率最低,其次为C组和B组,D组最高(P<0.05),A组新生儿情况最佳,其次为C组、B组和D组(P<0.05)。TRUST滴度<1:8时新生儿死亡率、先天梅毒以及产妇死胎、流产和早产率均低于TRUST滴度≥1:8时(P<0.05),不同滴度死产差异不显著(P>0.05)。结论:产妇妊娠结局受抗梅毒治疗以及TRUST滴度的影响,及早给予患病产妇进行治疗能够改善其妊娠结局。
OBJECTIVE: To analyze the effect of maternal pregnancy outcomes on anti-syphilis treatment and TRUST titer. Methods: The subjects were enrolled in our hospital for treatment of patients with gestational syphilis, as the experimental group, with different pregnant mothers during pregnancy as a group basis, the patients were divided into A group, B group, C, D, the same period in Healthy maternal health examination in our hospital as a control group. Results: The neonatal mortality rate and abortion rate in the control group were significantly lower than those in the experimental group (P <0.05). The incidence of adverse pregnancy in group A, B and C was significantly lower than that in group D (P <0.05), and the incidence of adverse pregnancy in group A was the lowest, followed by group C and group B, the highest in group D (P <0.05) Children were the best, followed by C, B and D (P <0.05). TRUST titers <1: 8 neonatal mortality, congenital syphilis and maternal stillbirth, abortion and premature birth rates were lower than the TRUST titer ≥ 1: 8 (P <0.05), different titer stillbirth difference was not significant (P > 0.05). CONCLUSIONS: Maternal pregnancy outcomes are influenced by anti-syphilis treatment and TRUST titer, and early treatment of sick mothers can improve their pregnancy outcomes.