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目的:比较妇血宁方药的水提和醇提工艺。方法:以提取液中黄芪甲苷、白术内酯Ⅰ、白术内酯Ⅲ、异阿魏酸、特女贞苷及细叶远志皂苷含量为指标,比较妇血宁方药的水提和醇提工艺。用HPLC法测定上述各指标成分的含量。结果:50%乙醇提取液中黄芪甲苷、白术内酯Ⅰ、白术内酯Ⅲ、异阿魏酸、特女贞苷及细叶远志皂苷含量均明显高于水提液。结论:妇血宁方药采用50%乙醇提取各指标成分提取量明显优于水提,为该方药的提取工艺研究提供了科学依据。
Objective: To compare the water extraction and alcohol extraction of Fuxuening Recipe. Methods: The contents of Astragaloside IV, atractylenolide I, atractylenolide III, isoferulic acid, lignostrobin and the extract of Polygonatum sibiricum were used as indexes to compare the water extraction and alcohol extraction of Fuxuoning Recipe . The HPLC method was used to determine the contents of above indexes. Results: The content of astragaloside, atractylenolide, atractyloside Ⅲ, isoferulic acid, levofloxacin and the extract of Polygala tenuifolia in 50% ethanol extract were significantly higher than that of water extract. Conclusion: The extract of Fuxuening Recipe by 50% ethanol is better than water extract by extraction, which provides a scientific basis for the extraction process of this recipe.