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反胃因其症状的特殊性,食谷不化,定时反出,而与呃逆、呕吐不同。在临床上常见而又易混淆,治疗上各个医家各有不同。而西医药亦未见高效、无反复的良好治疗方法。该研究基于中医传承辅助系统(V2.5)软件,分析和总结历代中医治疗反胃处方的用药规律,以期指导临床辨证用药,总结出治疗反胃的基本规律。筛选出《中医方剂大辞典》中治疗反胃的处方,运用中医传承辅助系统,采用频次分析、关联规则apriori算法及复杂系统熵聚类等数据挖掘方法,挖掘其中的用药规律。最终确定了处方的药物频次,得出使用频次较高的药物,发现药物之间的关联规则,得到常用药物组合19个,挖掘出10组核心组合与10首新处方,发现了反胃的基本病机为脾胃虚寒,胃失和降。历代医家治疗反胃处方用药以温中健脾,降逆和胃为主,主要治以生姜、人参、白术、茯苓、甘草等,适当配以燥湿化痰、理气和胃之品,并且依据反胃所形成的不同伴随证候痰、瘀、阴虚等,对证施治。
Nausea due to the special nature of their symptoms, eating fresh, regular anti-out, and unlike hiccups, vomiting. Common in clinical and confusing, the treatment of various physicians are different. Western medicine has not seen efficient, no repeated good treatment. Based on the TCM inheritance assistant system (V2.5) software, this study analyzed and summarized the medication rules of traditional Chinese medicine treatment of nausea prescription in order to guide the clinical use of dialectical medicine and summed up the basic rules of treating nausea. The recipe of treating nausea was screened from the Dictionary of TCM Prescriptions. The traditional Chinese medicine inheritance assistant system was adopted. The data mining methods such as frequency analysis, association rule apriori algorithm and complex system entropy clustering were used to explore the medication rules. Finally determine the frequency of the drug prescription, draw higher frequency of use of drugs, found that the association between drugs, 19 commonly used drug combinations, dig out 10 sets of core combinations and 10 new prescriptions, discovered the basic disease of nausea Machine for the spleen and stomach, loss of stomach and drop. Ancient medical treatment of nausea Prescription medication with warm in the spleen, Jiangni and stomach-based, the main rule of ginger, ginseng, Atractylodes, Poria, licorice, etc., accompanied by dampness and phlegm, Qi and stomach products, and based on the formation of nausea Different with syndrome phlegm, stasis, yin deficiency, etc., on the Syndrome.