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目的：探讨ＡｇＮＯＲ图像定量分析对针吸肝细胞癌及增生肝细胞的鉴别诊断价值。方法：应用真彩色图像分析技术对肝针吸细胞中的２０例肝癌及５例增生肝细胞核内ＡｇＮＯＲ进行了定量研究。结果：肝针吸癌细胞核内ＡｇＮＯＲ的平均面积、平均积分光密度、直径及平均颗粒数明显高于增生肝细胞（Ｐ＜０．０１）。结论：ＡｇＮＯＲ图像定量分析可为肝针吸癌细胞和增生肝细胞的鉴别诊断提供一种新的定量指标；ＡｇＮＯＲ在形态、数量及分布上的不同特征也可作为鉴别两者的重要依据。
Objective: To investigate the differential diagnostic value of AgNOR image quantitative analysis on needle-aspiration hepatocellular carcinoma and hyperplasia hepatocytes. Methods: Quantitative study of AgNOR in 20 cases of hepatocellular carcinoma and 5 cases of hyperplastic hepatocytes in liver aspirate cells was performed using true color image analysis. RESULTS: The mean area, average integral optical density, diameter and average number of particles in the nucleus of liver cancer cells were significantly higher than those in hyperplastic hepatocytes (P<0.01). Conclusion: AgNOR image quantitative analysis can provide a new quantitative index for differential diagnosis of liver aspirate cancer cells and hyperplastic hepatocytes; AgNOR’s different features in morphology, quantity and distribution can also be used as an important basis for identifying the two.