多原发癌(以下简称“MPC”),指一个宿主相同或不同的器官、组织同时或前后发生两个或以上不相关的原发恶性肿瘤。1889年经近代外科之父Billroth首次报道后,多原发癌逐渐被重视。本文就国内外文献报道多原发癌的研究作一综述。1流行病学特点近年国外报道MPC发病率为1.2%~10.7%,国内约0.4%~2.4%~([1])。MPC多为双原发,文献报 Multiple primary cancers (hereinafter referred to as “MPC”) refer to an organ of the same or a different host, with two or more unrelated primary malignancies occurring simultaneously or before and after the tissue. In 1889, after the first report of Billroth, the father of modern surgery, multiple primary cancers gradually came to be valued. This article reviews the reports of multiple primary cancers both at home and abroad. 1 epidemiological characteristics In recent years, foreign reports of MPC incidence of 1.2% to 10.7%, the domestic about 0.4% ~ 2.4% ~ ([1]). MPC mostly double primary, literature newspaper