本文报道了2例服用同一种中药浸酒治疗关节痛(张氏药酒)引起凝血时间、白陶土部分凝血活酶时间及血浆凝血酶原时间均明显延长的患者,临床上都有明显肉眼血尿及皮肤出血等表现,经输鲜血后治愈。动物实验证实此等药酒确有抗凝作用,可能由于缺乏维生素K依赖性凝血因子所致,能被静脉注射维生素K_1纠正。本文将初步研究结果予以报道。 This article reports 2 patients taking the same kind of Chinese herbal medicine immersion wine treatment of joint pain (Zhang wine) caused by clotting time, kaolin part of the thromboplastin time and plasma prothrombin time were significantly longer patients, clinically obvious gross hematuria and Skin bleeding performance, after the blood transfusion cured. Animal experiments confirmed that these wines do have anticoagulant effects, possibly due to the lack of vitamin K-dependent coagulation factors, which can be corrected by intravenous injection of vitamin K_1. This article reports the preliminary findings.