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目的观察奥美拉唑治疗消化道溃疡病变合并上消化道出血疾病的临床效果。方法选取2012年5月-2015年5月医院所接受的消化道溃疡病变合并上消化道出血患者90例,按就诊单双数顺序法分成研究组和对照组各45例,对照组采取雷尼替丁药物治疗,研究组采取奥美拉唑药物治疗;比较2组患者的临床治疗效果。结果研究组出血停止时间、大便隐血转阴时间、住院时间均比对照组患者短,差异有统计学意义(P<0.05);研究组治疗后的总有效率为91.1%高于对照组的71.1%,且其再出血率为6.7%低于对照组的20.0%,差异有统计学意义(P<0.05)。结论对消化道溃疡病变合并上消化道出血患者采取奥美拉唑进行治疗,效果明显,再出血率低,住院时间短,值得在临床上大力推行与运用。
Objective To observe the clinical effect of omeprazole in the treatment of upper gastrointestinal bleeding in patients with peptic ulcer disease. Methods From May 2012 to May 2015, 90 patients with peptic ulcer disease and upper gastrointestinal bleeding accepted by the hospital were divided into study group (45 cases) and control group (45 cases) according to single and double order of treatment. The control group For drug treatment, the study group to take omeprazole drug treatment; comparison of two groups of patients with clinical treatment. Results The bleeding stop time, occult blood overtaxing time and hospital stay in study group were shorter than those in control group (P <0.05). The total effective rate in study group was 91.1%, which was higher than 71.1% in control group %, And the rate of rebleeding was 6.7% lower than 20.0% of the control group, the difference was statistically significant (P <0.05). Conclusions Omeprazole is an effective treatment for patients with gastrointestinal ulcer and upper gastrointestinal hemorrhage. The effect is obvious, the rate of rebleeding is low and the hospitalization time is short, which is worth to be vigorously promoted and applied clinically.