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目的:在调查深圳地区不同等级医院-临床合理用药现状的基础上,探索促进合理用药的工作模式。方法:选择6家不同等级医院2年各2个月门诊处方和当日门诊就医患者,采取多中心、随机试验方法,对合理用药国际指标的核心指标进行干预前后的现场调查,并用SPSS13.0软件进行统计分析。结果:干预组自身对比平均用药品种数从2.44种降到2.14种(P<0.05);抗生素使用百分率从43.7%降到35.7%(P<0.01);注射剂使用百分率从22.3%降到17.5%(P<0.01);患者了解正确用药方法百分率从96.7%上升到100%;干预后指标好于干预前。结论:使用WHO & INRUD开发的合理用药指标(SDU- Is)评价和比较不同医疗单位用药状况具有可行性和有效性。通过宣传教育、完善规章制度和加强监督检查等策略进行干预性研究具有可操作性。
Objective: To investigate the current situation of different levels of hospitals in Shenzhen - the rational use of drugs on the basis of exploration to promote rational use of the working model. Methods: Six outpatient prescriptions and outpatients were enrolled in two different hospitals in two different years for 2 years. A multicenter randomized trial was conducted to investigate the core indicators of international indicators of rational drug use before and after intervention. SPSS 13.0 software conduct statistical analysis. Results: Compared with the control group, the average number of drug users in the intervention group decreased from 2.44 to 2.14 (P <0.05), the percentage of antibiotics decreased from 43.7% to 35.7% (P <0.01), and the percentage of injections decreased from 22.3% to 17.5% P <0.01). The percentage of patients who knew the correct medication increased from 96.7% to 100%, and the index after intervention was better than that before intervention. Conclusion: It is feasible and effective to use the SDU-Is developed by WHO & INRUD to evaluate and compare the medication status of different medical units. It is feasible to carry out intervention research through strategies such as publicity and education, improvement of rules and regulations and enhancement of supervision and inspection.