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形态学上 ,正常成人肾脏间质的纤维结缔组织很少 ,肾小管之间仅有少量间质分割。肾脏间质对维护正常肾功能非常重要。间质纤维化、肾小球硬化、动脉硬化是老年人肾脏的特征性形态改变〔1〕。间质纤维化也是造成老年人肾功能储备不足或低下的重要原因。转化生长因子 (Ｔｒａｎｓ
Morphologically, the normal adult renal interstitial fibroarticular few, only a small amount of tubulointerstitial segmentation. The renal interstitium is very important for the maintenance of normal kidney function. Interstitial fibrosis, glomerulosclerosis, arteriosclerosis is the characteristic morphological changes in the elderly kidney [1]. Interstitial fibrosis is also an important cause of insufficient or low renal reserve in the elderly. Transforming growth factor (Trans