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从一个痴呆伴严重淀粉样血管病 (ＣＡＡ)的Ｉｏｗａ家系中鉴定出一个新的淀粉样蛋白前体 (ＡＰＰ)基因点突变 [英 ]/ＧｒａｂｏｗｓｋｉＪ… /ＡｎｎＮｅｕｒｏｌ 2 0 0 1;49:6 97～ 70 5ＡＰＰ基因的几种突变与 β -淀粉样肽 (Ａβ)病理性沉积于神经纤维与血管壁而祸害人类
A new point mutation in the amyloid precursor (APP) gene was identified in a family of Iowa with dementia with severe amyloid angiopathy (CAA). / Grabowski J ... / Ann Neurol 2 0 0 1; 49: 6 97 ~ Several mutations of the 5APP gene and the deposition of β - amyloid peptide (Aβ) pathologically in nerve fibers and blood vessel walls are harmful to humans