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目的:观察中西医结合治疗冠心病心绞痛的临床疗效。方法:238例冠心病心绞痛患者,随机分为对照组和治疗组。对照组给常规应用阿司匹林、β-阻滞剂、硝酸酯类药物和(或)钙拮抗剂治疗。治疗组在对照组治疗的基础上,以补阳还五汤为主方,根据病情随证加减治疗。疗程均为3月。观察临床疗效、心电图、血脂[总胆固醇(TC)、甘油三酯(TG)、高密度蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)]、血液流变学等变化。结果:临床总有效率治疗组95.83%,对照组65.25%,2组比较,差异有统计学意义(P<0.01)。心电图总有效率治疗组76.67%,总有效率48.31%,2组比较,差异有统计学意义(P<0.01)。治疗组治疗后TC、TG、HDL-C、LDL-C与治疗前比较,差异均有统计学意义(P<0.01);治疗后2组TC、TG、HDL-C、LDL-C比较,差异均有统计学意义(P<0.01)。治疗组治疗前后全血黏度高切、中切、低切和血浆黏度,纤维蛋白原比较,差异均有统计学意义(P<0.01);治疗后各项指标2组比较,差异均有统计学意义(P<0.01)。结论:冠心病心绞痛在西药常规治疗的的基础上,加用补阳还五汤治疗,可以更有效的消除临床症状,改善心肌缺血、血脂及血液流变学等。
Objective: To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of angina pectoris. Methods: 238 patients with coronary heart disease angina pectoris were randomly divided into control group and treatment group. The control group was given routine treatment with aspirin, beta-blockers, nitrates and / or calcium antagonists. The treatment group in the control group based on the treatment, with Buyanghuanwu Tang as the main prescription, according to the disease with card plus treatment. Treatment are March. The changes of clinical curative effect, electrocardiogram, blood lipid [total cholesterol (TC), triglyceride (TG), HDL-C, LDL-C and hemorrheology were observed. Results: The total clinical effective rate was 95.83% in the treatment group and 65.25% in the control group. There was significant difference between the two groups (P <0.01). The total effective rate of ECG in treatment group was 76.67%, the total effective rate was 48.31%. There was significant difference between two groups (P <0.01). The levels of TC, TG, HDL-C and LDL-C in the treatment group after treatment were significantly different from those before treatment (P <0.01). The TC, TG, HDL-C and LDL- All were statistically significant (P <0.01). The whole blood viscosity of the treatment group before and after the high-cut, cut, low cut and plasma viscosity, fibrinogen, the difference was statistically significant (P <0.01); after treatment, the two groups of indicators, the difference was statistically Significance (P <0.01). Conclusion: Coronary heart disease angina pectoris can be more effective in eliminating clinical symptoms, improving myocardial ischemia, blood lipids and hemorheology on the basis of routine treatment of western medicine plus BYHWD treatment.