为什么有时人体会把Ach受体作为自体抗元来对待呢?回答可能在于与胸腺疾病的关系。75%重症肌无力患者有胸腺增生;10-15%患者有胸腺瘤。胸腺无论来自肌无力患者与否,其上皮细胞都具有Ach受体。而且部分学者肯定胸腺细胞在组织培养中有发展成为横纹肌样细胞的势能。一个假说认为之所以易患重症肌无力取决于胸腺细胞呈现引起免疫反应新抗元那种遗传决定的倾向。某些种族的小鼠在控制整个组织配型性复合体点联结的基因下,胸 Why do people sometimes think of Ach receptors as self-antigens? The answer may lie in the relationship with thymic diseases. 75% of myasthenia gravis patients with thymus hyperplasia; 10-15% of patients with thymoma. The thymus, whether from myasthenic patients or not, has epithelial cells with Ach receptors. And some scholars affirm thymocytes in tissue culture have developed into striated muscle-like cells potential. One hypothesis is that the predisposition to myasthenia gravis depends on the genetic predisposition of the thymus to elicit new anti-immune responses. Some ethnic mice under the control of the entire organization of sex complexes complex point junction genes, chest