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活血化瘀中药川芎嗪具有保护放射及免疫损伤造血微环境的作用[1,2]。我们建立了同基因骨髓移植小鼠模型,探讨川芎嗪在造血干细胞移植骨髓造血重建中的作用及其机制,为寻找促进造血干细胞移植后骨髓重建造血的治疗方法提供科学依据。材料和方法1 实验动物 清洁级近交系ＢＡＬ
Ligustrazine has the function of protecting the hematopoietic microenvironment of radiation and immune injury [1,2]. We established a mouse model of syngeneic bone marrow transplantation to investigate the role of ligustrazine in the hematopoietic reconstitution of hematopoietic stem cell transplantation and its mechanism, to provide a scientific basis for the search for a method to promote bone marrow reconstitution and hematopoiesis after hematopoietic stem cell transplantation. Materials and Methods 1 Laboratory animal clean-up inbred BAL