欧阳等对台湾尖吻蝮蛇毒进行分离纯化,并对类凝血酶组分进行系统研究后指出,类凝血酶具有去纤维蛋白原作用,能使血液产生低凝状态. 张洪基以及李麟仙等对大陆尖吻蝮蛇毒进行分离纯化,研究了“去纤酶”的体内抗凝血作用,对大鼠动静脉实验性血栓的形成有预防效应. 本文报导家兔静注尖吻蝮(Agkistrodn acutus)类凝血酶对体外血栓形成的影响进行研究,认为药效满意. Ouyang et al. performed isolation and purification of venomous venom of Taiwan venom, and pointed out that thrombin-like substances have a defibrinogen effect and can cause blood to have a low coagulation state. Zhang Hongji and Li Linxian et al. The isolated anti-coagulant effect of “defibrase” was studied by isolation and purification of the snake venom venom, which could prevent the formation of arteriovenous experimental thrombus in rats. This paper reports Agkistrodn acutus coagulation in rabbits. The effect of enzymes on thrombosis in vitro was studied and it was considered that the efficacy was satisfactory.