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小儿难治性’肾病综合征（N）目前尚无满意的治疗方案．我们于1993－01～1998－12对各种激素耐药以及激素依赖，反复复发的顽固性NS，采用大剂量环磷酸胺冲击疗法（HD－CTX－PT）治疗、32例，取得满意疗效，现报道如下．l对象和方法1．l对象顽固性NS患儿32例，男22例，女10例；
Pediatric refractory nephrotic syndrome (N) There are currently no satisfactory treatment options. In 1993-01 ~ 1998-12, we treated 32 patients with intractable NS with various hormone resistance and hormone dependence and repeated relapse by high dose cyclophosphamide impact therapy (PT-PTX), and achieved satisfactory results. Report as follows now. l objects and methods 1. l object stubborn NS children 32 cases, 22 males and 10 females;