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目的:探讨内脏脂肪厚度与非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)的关系.方法:选择进行健康体检的人员共170例;分成两组:即非酒精性脂肪性肝病组110例(分轻度40例、中度40例和重度30例),健康对照组60例.入选者空腹检查血压、身高、体质量、臀围、腰围、甘油三脂、总胆固醇、血糖、肝功能、血胰岛素水平,计算体质量指数(body massindex,BMI)、腰臀比(waist-hip ratio,WHR)、胰岛素抵抗指数(homeostasis model assessmentHOMA-IR).超声测量内脏脂肪厚度.结果:非酒精性脂肪性肝病组的B M I、WHR、HOMA-IR、内脏脂肪厚度等指标与健康对照组相比较均增高,差异存在统计学意义(P<0.05).内脏脂肪厚度在轻度、中度、重度非酒精性脂肪性肝病各组中两两比较差异均有统计学意义.相关分析显示,内脏脂肪厚度与BMI、WHR、HOMA-IR等呈正相关(r值依次为0.62、0.509、0.596,均P<0.05).结论:超声测定内脏脂肪厚度可作为评价非酒精性脂肪性肝病的一项重要指标.
Objective: To investigate the relationship between visceral fat thickness and nonalcoholic fatty liver disease (NAFLD) .Methods: A total of 170 patients were selected for physical examination. They were divided into two groups: 110 patients with non-alcoholic fatty liver disease (40 cases in mild, 40 cases in moderate and 30 cases in severe) and 60 cases in healthy control group.The blood pressure, height, body weight, hip circumference, waist circumference, triglyceride, total cholesterol, blood sugar, liver function , Blood insulin level, body mass index (BMI), waist-hip ratio (WHR) and homeostasis model assessment (HOMA-IR) were calculated.Results: Non-alcoholic The indexes of BMI, WHR, HOMA-IR, visceral fat thickness in fatty liver disease group were all higher than those in healthy control group (P <0.05) .The visceral fat thickness was significantly higher in mild, moderate and severe non- Alcoholic fatty liver disease in each group in any pairwise differences were statistically significant.Related analysis showed that visceral fat thickness and BMI, WHR, HOMA-IR was positively correlated (r values were 0.62,0.509,0.596, P < 0.05) .Conclusion: Ultra Acoustic determination of visceral fat thickness can be used as a non-alcoholic fatty liver disease is an important indicator.