有人报告口服避孕药可以使月经前忧郁症状减轻,但是有一些妇女却相反地出现严重的忧郁情况.虽然Goldzieher认为这是心理作用的结果,但看来内分泌变化的作用不容忽视.按照脑胺假说看来,情绪与血清素及去甲肾上腺素有关,特别是它们浓度的相互比率更为重要.有人认为避孕药的孕酮成份较多者易于引起忧郁,因孕酮可增加子宫内膜的单胺氧化酶(MAO)活力,由此推测也可增加脑内MAO活力,从而改变脑胺浓度之故.但也有人认为情况正好相反.正常人体内色胺酸代谢有二途径:一是从犬尿素直至烟酸,一是转变为血清素.服用避孕药者尿 It has been reported that oral contraceptives can reduce the symptoms of premenstrual depressive symptoms, but some women, on the contrary, experience severe depression.Although Goldzieher considers this a psychological result, it appears that the role of endocrine changes can not be ignored.According to the brain amine hypothesis It seems that emotions and serotonin and norepinephrine related, in particular, the mutual ratio of their concentration is more important.Some people think that more progesterone contraceptives prone to depression, progesterone can increase endometrial monoamine oxidase (MAO) activity, which speculated that can also increase intracerebral MAO activity, thus changing the concentration of meningitis. However, some people think the opposite. Normal human tryptophan metabolism in two ways: First, from dog urea until smoke Acid, one is converted to serotonin. Take contraceptives urine