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探讨孕妇巨细胞病毒、弓形虫感染率和胎儿传播率以及与胎儿畸形的关系。方法：随机选择2000例不同职业孕妇，采用PCR技术对其外周血及配对胎儿脐血进行CMV、弓形虫检测。结果：孕妇CMV阳性率4．05％（81／2000），弓形虫阳性率2．15％（43／2000），配对脐血CMV阳性率1％（20／2000），弓形虫阳性率0．7％．母婴传播率分别为20／81，14／43。具有异常妊娠史孕妇CMV感染率12．3％（35／283）．弓形虫感染率7．07％（20／283），与无异常妊娠史孕妇（2．68％，46／1717）；（1．34％，23/1717）比较，差异显著（P＜0．01）。124例CMV、弓形虫感染孕妇发生胎儿畸形7例（5．64％），无感染1876例孕妇发生胎儿畸形48例（2．56％），两组比较差异显著（P＜0．05）。结论：孕妇CMV、弓形虫感染危害较为严重，易导致流产、致畸等。开展对孕妇CMV、弓形虫感染检测，进行早期诊断．有利于优生优育工作。
To explore the relationship between maternal cytomegalovirus, Toxoplasma gondii infection rate and fetal transmission rate and fetal malformations. Methods: Two hundred and seventy pregnant women of different occupations were randomly selected. CMV and Toxoplasma gondii were detected by PCR in peripheral blood and paired cord blood. Results: The positive rate of CMV in pregnant women was 4.05% (81/2000), the positive rate of Toxoplasma gondii was 2.15% (43/2000), the positive rate of CMV in matched cord blood was 1% (20/2000), and the positive rate of Toxoplasma gondii was 0. 7%. The rates of mother to child transmission were 20/81 and 14/43, respectively. The pregnant women with abnormal pregnancy history CMV infection rate was 12.3% (35/283). The infection rate of Toxoplasma gondii was 7.07% (20/283), which was significantly different from that of pregnant women without abnormal pregnancy (2.68%, 46/1717) (1.34%, 23/1717) (P <0.05). 01). Among 124 pregnant women with CMV and Toxoplasma gondii infection, 7 cases (5.64%) had fetal malformations, and 48 cases (2.56%) had fetal malformations with 1876 pregnant women without infection. There were significant differences between the two groups (P <0.05). Conclusion: Pregnant women CMV, Toxoplasma gondii infection more serious, easily lead to miscarriage, teratogenicity and so on. To pregnant women CMV, Toxoplasma gondii infection detection, early diagnosis. Good for prenatal and postnatal care work.