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传统认为,常温下脑耐受缺血、缺氧的时间为5min,超过此时限,心、肺功能虽可能恢复,而脑的功能则可能部分或全部受到损害.因此循环骤停前后如何做好脑保护及脑复苏,于七十年代初即已受到重视.Hossmann的试验观察表明,经过脑复苏的措施,机体耐受循环停止的时间可延长3～4倍,甚至60min,给脑复苏的研究提供希望.近年来Safar教授在脑复苏的研究中提出“复苏后症候群”并对于其病理生理的改变,即脑灌注衰竭、脑再氧合的损害等问题,进行了大量的研究,取得可喜的进展,在此基础上,脑复苏的临床效果,可望得到显著提高.
Traditionally, the brain tolerates ischemia and hypoxia at normal temperature for 5 min, beyond which time the heart and lung function may recover, whereas the brain function may be partially or totally compromised. Therefore, how to do well before and after the cycle arrest Brain protection and brain resuscitation, has been taken seriously in the early seventies.Hossmann’s experimental observations show that after the brain resuscitation measures, the body can tolerate the cycle to stop extending the time can be prolonged 3 to 4 times, or even 60min, to cerebral resuscitation In recent years Professor Safar in the study of brain resuscitation put forward “post-recovery syndrome” and for its pathophysiology changes, cerebral perfusion failure, damage of brain reoxygenation and other issues, a lot of research and achieved gratifying On the basis of this, the clinical effect of cerebral resuscitation is expected to be significantly improved.